Math Biology Seminar: The Min system in E.coli: A stochastic polymer model and new ideas for experiments
- Date: 09/22/2009
University of British Columbia
The Min system in E.coli: A stochastic polymer model and new
ideas for experiments
The Min system in E.coli -- a group of three interacting proteins
playing a role in cell division -- has attracted a lot of attention by
modellers, some claiming it to be the 'measurement stick' in the
rod-shaped bacterium. Different models have been proposed to explain the
observed dynamical patterns -- oscillations, standing and travelling
waves. Here, we will focus on a simple polymerisation/depolymerisation
model. The model provides an interesting example of a stochastic hybrid
dynamical system and we use probabilistic maps to compute probability
distributions of experimentally accessible quantities. As a step towards
model discrimination I will report on experiments we conducted on
GFP-labelled E.coli.
2:00pm-3:00pm, WMAX 110
For details, please visit the official website at:
