Which 3-manifolds smoothly embed in the 4-sphere? This seemingly simple question turns out to be rather subtle. Using Donaldson's theorem, we derive strong restrictions to embedding a Seifert fibered space over an orientable base surface, which in particular gives a complete classification when e is greater than k/2, where k is the number of exceptional fibers and e is the normalized central weight. Our results point towards a couple of interesting conjectures which I'll discuss.
This is joint work with Duncan McCoy.