Modelling aspects of solid tumour growth
- Date: 04/19/2012
- Time: 14:30
Prof. Philip Maini
Prof. Philip Maini is Director of the Centre for Mathematical Biology, University of Oxford, UK
He
co-authored a Bellman Prize winning paper (1997), was awarded a Royal
Society Leverhulme Trust Senior Research Fellowship for 2001-2 and a
Royal Society-Wolfson Research Merit Award (2006-11). In 2009 he was
awarded the LMS Naylor Prize and Lectureship.
University of Victoria
Modelling aspects of solid tumour growth
Abstract:
This talk will present a range of mathematical modelling approaches we have
used recently to model aspects of solid tumour growth. We will consider a
very simple ordinary differential equation model for homeostasis in
intestinal crypts, a more complicated cell-based hybrid model for crypt
dynamics, a partial differential equation model for the acid-mediated
invasion hypothesis and a compartmental model for acid-buffer handling
in the body. Results from the mathematical analyses will be interpreted
in the biological context to try to shed light on some fundamental
processes and suggest therapies.