UBC Math Bio: Mingfei Qiu

  • Date: 10/05/2022
  • Time: 14:00
Mingfei Qiu, École Normale Supérieure, Paris

University of British Columbia


Actomyosin cables by mechanical self-organization [video]


Supracellular actomyosin cables often drive morphogenesis in development. The origin of these cables is poorly understood. We show theoretically and computationally that under external loading, cell-cell junctions capable of mechanical feedback could undergo spontaneous symmetry breaking and establish a dominant path through which tension propagates, giving rise to a contractile cable. This type of cables transmit force perturbation over a long range, and can be modulated by the tissue properties and the external loading magnitude. Our theory is general and highlights the potential role of mechanical signals in guiding development.

Other Information: 

Location: Online

For Zoom link, please contact Katie Faulkner (kfaulkner@math.ubc.ca).

This event took place via zoom, a recording is available on mathtube.org.