Math Biology Seminar: Gautam I. Menon

  • Date: 09/10/2015
  • Time: 14:00
Gautam I. Menon, Institute of Mathematical Sciences, Chennai, India

University of British Columbia


Crowding: Why it might not be a bad idea after all


Cells provide highly crowded environments for the processes governing life to play out. We have been exploring some contexts, involving the transport of vesicle-encapsulated material down axons in nerve cells, where crowding appears to be crucial to healthy function. I will discuss how and why this might happen, describing some subtleties that must be accounted for when cellular motor-driven transport is modelled. Our work suggests that the robustness of cargo transport in crowded environments is an emergent property of the interaction of cargo vesicles with other vesicles as well as with crowding elements, and thus depends crucially on the milieu in which such vesicles move.This is joint work with the laboratory of Sandhya Koushika of TIFR, Mumbai and centres around a close collaboration between computational modelling and experiment.

Other Information: 

Location: ESB 4133