Jay Newby

A collection of identical and independent rare event first passage times is considered. The problem of finding the fastest out of $N$ such events to occur is called an extreme first passage time. The rare event times are singular and limit to...

Abstract: The principal function of the nucleus is to facilitate storage, retrieval, and maintenance of the genetic information encoded into DNA and RNA sequences. A unique feature of nucleoplasm—the fluid of the nucleus—is that it contains chromatin...

Abstract: We study stochastic motion of objects in micrometer-scale living systems: proteins in the nucleus, organelles in cells, and pathogens in mucus barriers. Phenomena such as self organization emerges from the behavior of single individuals...

The data association problem is the difficult part of the multi-object tracking problem. The problem is to: (i) classify measurements (e.g., position, shape, etc) as true positives or false positives, ( ii) classify tracked objects as observed (i.e...

The longstanding view in chemistry and biology is that high-affinity, tight-binding interactions are optimal for many essential functions, such as receptor-ligand interactions. Yet, an increasing number of biological systems are emerging that...

Molecular crowding has recognized consequences for biological function. However, there are also circumstances in which un-crowding is important that is, when molecules must evacuate from a region before a given process can occur. One example is...