Anmar Khadra

Recent experimental observations have revealed that during the onset of autoimmune Type 1 Diabetes (T1D), different clones of T cells with various T cell avidities and protein specificities are naturally generated in diabetic animal models. One...

One major scientific challenge in human health is developing effective vaccines to block T-cell responses in spontaneous autoimmune disorders, such as type 1 diabetes (T1D). The ability of these T cells to recognize host cells (e.g., insulin...

Cellular movement plays important roles in many (patho)physiological processes, such as immune cell response, growth of neuronal axons and cancer. The regulation of this movement depends on the interaction of several key proteins implicated in the...