Detecting Spillover: A dynamical systems modeling approach to glutamatergic synaptic signaling

  • Date: 02/27/2007

Emily Stone (University of Montana)


University of British Columbia


The connectivity of neurons in the hippocampus depends in part on
whether neurotransmitter from one release site can leak out and
activate receptors in another synapse or extrasynaptic patch. The
existence of such 'spillover' is under debate in the neuroscience
community, since direct measurements of neurotranmitter in such detail
cannot, as of yet, be made. Experimental evidence of spillover is thus
indirect, and should be sifted through as many different filters as
possible. In this talk I present the contributions of dynamical systems
modeling to this effort.

Other Information: 

SCAIM Seminar 2007