IAM-PIMS Distinguished Colloquium: Paul K. Newton

  • Date: 02/24/2014
  • Time: 15:00
Paul K. Newton, Department of Aerospace & Mechanical Engineering and Mathematics, Viterbi School of Engineering, University of Southern California

University of British Columbia


Random Walks, Markov Chains, and Cancer Metastasis Models


The talk will describe a recent mathematical/computational model for understanding aspects of cancer metastasis, initiated when primary tumor cells enter the vasculature and lymphatic system becoming circulating tumor cells (CTC's).  The model is based on a Markov chain dynamical system designed so that the transition matrix has as it's steady-state a `target' vector obtained from an autopsy data set.  The target vector, chosen for a given type of primary cancer (i.e. lung), contains the distribution of metastatic tumors from an ensemble population.

Other Information: 

Location: LSK 460