Mathematical Biology Seminar: Michael Rempe

  • Date: 02/16/2012
  • Time: 14:00
Michael Rempe

University of British Columbia


A mathematical model of human sleep and insomnia




I will present a biologically-based mathematical model that accounts for several features of human sleep and demonstrate how particular features depend onĀ  interactions between a circadian pacemaker and a sleep homeostat. The model is made up of regions of cells that interact with each other to cause transitions between sleep and wake as well as between REM and NREM sleep. Analysis of the mathematical mechanisms in the model yields insights into potential biological mechanisms underlying sleep and sleep disorders including stress-induced insomnia and fatal familial insomnia.

Other Information: 

Location: WMAX 110


For more information please visit UBC Mathematics Department