Scientific General Events
Cellular reconstitution: Rebuilding biological systems from the bottom-up
Abstract:Understanding the molecular basis of cellular behaviour is a central goal in biology and a critical guide for medical research. Increasing knowledge of the essential proteins in a complex process such as crawling motility raises the tantalizing question: Do we know enough to build it? In vitro reconstitution provides an import tool for identifying the roles of individual molecules, but defining components is not enough. Progress towards reconstitution of micron-scale cellular structures and processes has been limited by the challenges of generating in vitro reconstitutions that capture the spatial organization, physical constraints, and dynamics of living cells. This talk will describe on-going efforts to create functional reconstitutions of cytoskeletal and membrane processes involved in cellular protrusions and membrane transport. The lessons of what works – and what doesn’t – are helping to guide efforts to build biological systems from molecular parts.
Topics in this session include:
Some simple triangulations
Twist knots and the uniform thickness property
Right-angled Coxeter polytopes, hyperbolic 6-manifolds, and a problem of Siegel
Geometric representatives of homology classes in the space of knots
+ more topics to follow
Please consult the attachement
Two needles in exponential haystacks
Circular Distributions and Fisheries Models
On Friday October 14, 2011, we are holding the Pacific Northwest Seminar in honour of Dr. Bill Reed who retired from the University of Victoria on July 1, 2011. The seminars will focus on two areas that Bill has worked in: assessing goodness-of-fit and applied statistics. Michael Stephens will offer a theoretical discussion of assessing the fit of circular distributions and emerging issues in this field. Jon Schnute will discuss applied fisheries models and will look at what further research is required in this area.
The Langevin process and the trace formula.
Buffon's needle probability for rational product Cantor sets
combinatorics, algebraic topology, algebraic geometry, and applications