PIMS/UBC Distinguished Colloquium: Linda Petzold
- Date: 03/28/2014
University of British Columbia
The Emerging Roles and Computational Challenges of Stochasticity in Biological Systems.
In recent years it has become increasingly clear that stochasticity plays an important role in many biological processes. Examples include bistable genetic switches, noise enhanced robustness of oscillations, and fluctuation enhanced sensitivity or “stochastic focusing". Numerous cellular systems rely on spatial stochastic noise for robust performance. We examine the need for stochastic models, report on the state of the art of algorithms and software for modeling and simulation of stochastic biochemical systems, and identify some computational challenges.
Location: ESB 2012